Dectin - 1 Fc targeting of Aspergillus fumigatus beta - glucans 8 augments innate defense against invasive pulmonary aspergillosis 9 10 11 12
نویسندگان
چکیده
42 43 Invasive pulmonary aspergillosis (IPA) has significantly increased over the last decade. Here, a 44 fusion protein consisting of the Dectin-1 extracellular domain linked to the Fc portion of murine IgG1 45 augmented alveolar macrophage killing of A. fumigatus and shifted mortality associated with IPA via 46 attenuation of A. fumigatus lung growth. 47 48 49 50 51 52 53 54 55 56 57 58
منابع مشابه
The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus
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